The videos and companion resources below are designed to help investigators and study teams successfully plan for and navigate single IRB review arrangements for their studies. Questions about local processes and policies are best addressed by your institution’s SMART IRB Point of Contact.
SMART IRB Start-Up Packages
These packages contain a suite of resources to help you prepare NIH grant applications that require single IRB review and to ensure you understand and can fulfill your responsibilities related to single IRB arrangements. Each package provides a guide describing how and when to use the included resource as well as links to online tools and further information.
Introduction to Single IRB Review and SMART IRB
Learn about single IRB (sIRB) review and find out how SMART IRB can help you meet sIRB requirements.
Key Resources
- Joining SMART IRB
- SMART IRB Online Reliance System: request, track, and document reliance arrangements on a study-by-study basis.
- FAQs for Research Teams - Relying on an External IRB
Overview of the NIH Single IRB Policy
Learn about the NIH Single IRB Policy and what you need to address in funding applications for multisite research.
Selecting a Single IRB
Learn about the options for selecting a single IRB for your funding application.
Key Resources
- SMART IRB Online Reliance System: request, track, and document reliance arrangements on a study-by-study basis.
- FAQs for Research Teams - Relying on an External IRB
Developing a Single IRB Plan
Learn about the options for selecting a single IRB for your funding application.
Potential Effects of NIH Single IRB Policy on Research Costs
Find out how the NIH single IRB policy can affect research costs related to IRB review, staffing, and resources, and learn how to address these costs in your funding application.
Study Team Roles Related to Single IRB
Learn about key study team roles, responsibilities, and communication structures required for single IRB review.
Key Resources
- Communication Plan for Single IRB Review
- FAQs for Research Teams - Relying on an External IRB
- Overall PI (and Lead Study Team) Checklist
- Relying Site Investigator Checklist
- Informed Consent Documents: Inserting Local Context Language
- Relying Site Study Team Survey
- Single IRB Readiness Checklist for Lead Study Teams & Coordinating Centers
Using the SMART IRB Online Reliance System
Learn how to request, track, and document reliance arrangements for your studies using the SMART IRB Online Reliance System.
