Supporting single IRB review
    Advancing collaborative research

Investigators: Get Started

Use SMART IRB to enable single IRB review.

A monthly community forum
September 18:
Getting Ready for the 2020 Single IRB requirements
Past Sessions:
Harmonization - Reportable Events
Stay tuned for future SMART Talk topics.
On Demand Learning
Getting Started with the Online Reliance System
Implementing the SMART IRB Agreement
Responsibilities of Relying Institutions
Serving as a Reviewing IRB
Resources for IRB and HRPP Personnel
Join our mailing list to be notified of upcoming learning opportunities.

SMART IRB is a platform designed to ease common challenges associated with initiating multisite research and to provide a roadmap for institutions to implement the NIH Single IRB Review policy (effective date: January 25, 2018). Freely available for institutions and investigators, SMART IRB is an integrated, comprehensive platform that allows flexibility in the size and scope of collaboration to enable IRB reliance for multisite studies across the nation, regardless of funding status.

A roadmap to single IRB review

singlesource icon First step: Join SMART IRB
Streamline IRB review for multisite studies and eliminate the time and effort of negotiating IRB authorization agreements for each new study. Learn more about joining today.

online sharing icon Start Using the Online Reliance System for your studies
The Online Reliance System allows investigators and institution POCs to request, track, and document reliance arrangements on a study-by-study basis. Get started.

guidance icon Check out our SOPs, Templates, and Checklists
See our Resources page for a growing library of educational materials, tools, and checklists.

expertise icon Access Expertise across the Nation
Connect with a SMART IRB ambassador in your region. Institutions and IRBs can also request guidance through our consultation service.

Joining and using the SMART IRB platform is free; however, some institutions may charge IRB fees in connection with IRB Review activities.

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