Investigators: Submit/view a reliance request on the Online Reliance System.
IRB/HRPP Staff: Update institution information in Joinder; view pending requests in the Online Reliance System.
SMART IRB is a platform designed to ease common challenges associated with initiating multisite research and to provide a roadmap for institutions to implement the NIH Single IRB Review policy (effective date: January 25, 2018). Freely available for institutions and investigators, SMART IRB is an integrated, comprehensive platform that allows flexibility in the size and scope of collaboration to enable IRB reliance for multisite studies across the nation, regardless of funding status.
A roadmap to single IRB review
First step: Institutions join the SMART IRB Agreement
Streamline IRB review for multisite studies and eliminate the time and effort of negotiating IRB authorization agreements for each new study. Learn more about joining today.
Start Using the Online Reliance System for your studies
The Online Reliance System allows investigators and institution POCs to request, track, and document reliance arrangements on a study-by-study basis. Get started.
Check out our SOPs, Templates, and Checklists
Browse our Resources or visit the Learning Center for Investigators and for IRB/HRPP Administrators to access training videos, start-up packages, and more.
Access Expertise across the Nation
Connect with a SMART IRB ambassador in your region. Institutions and IRBs can also request guidance through our consultation service.
Joining and using the SMART IRB platform is free; however, some institutions may charge IRB fees in connection with IRB Review activities.
Subscribe to the Mailing List
Stay up to date on news, resources, and educational offerings.
A monthly community forum
Exploring the Financial Aspects of Single IRB
Watch past SMART Talks and access webinars, slides, and related resources in the Learning Center.
SMART IRB Agreement v2.0
Participating Institutions may now sign SMART IRB Agreement V2.0. Any new institutions will automatically sign SMART IRB Agreement V2.0.
Learn more about the revisions to the Agreement, or visit the Join page to get started.