0 Participating Institutions including all CTSA hubs

Reliance System: Log In
Reliance System: Log In
Reliance System: Log In

Important Update
On April 14, the NIH sent Harvard University a Stop Work Order of the SMART IRB federal funding contract.
From the beginning, SMART IRB has been a collaborative, grassroots effort: SMART IRB was built by and for the community. It is not owned by Harvard, NIH, HHS, or any other entity.  At this time, Harvard is supporting the core team to maintain the Agreement and assist Participating Institutions to the best of our abilities. It is our intention to continue to provide this vital support to advance collaborative research. Please contact us for assistance.
Read Full Statement

Search

User Guides

Download Determination Letter

1. Click” All Requests” on left hand navigation.  

2. From user dashboard select request that is in reliance reached. You can use the reliance reached card to filter your dashboard view. 

3. Select ” request activity”. 

4. Across from your site name select “download”. 

5. Determination letter downloads in pdf format. 

Participating Institutions
Reliance Agreement
Reliance System
Harmonization
Resource Library

Investigators & Study Teams
IRB and HRPP Administrators
About Us
Contact Us

Subscribe to the Mailing List

Stay up to date on news, resources, and educational offerings.

Copyright ©2025 The President and Fellows of Harvard College

If you require any of our publications, videos, or website content in an accessible format, please email us.