Important Update
On April 14, the NIH sent Harvard University a Stop Work Order of the SMART IRB federal funding contract.
From the beginning, SMART IRB has been a collaborative, grassroots effort: SMART IRB was built by and for the community. It is not owned by Harvard, NIH, HHS, or any other entity.  At this time, Harvard is supporting the core team to maintain the Agreement and assist Participating Institutions to the best of our abilities. It is our intention to continue to provide this vital support to advance collaborative research. Please contact us for assistance.
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Reliance System

User Guides

Step-by-step guidance for study teams and POCs

General Info

Freely available for institutions and investigators, the SMART IRB Reliance System allows institutions to join the SMART IRB Agreement and helps study teams and IRB/HRPP staff work together to seamlessly request, track, and document reliance arrangements with other Participating Institutions.

User Guides

Study Teams

Learn how investigators and study team members can centrally request, track, and document reliance arrangements for their studies.

Points of Contact (POCs)

Learn how IRB/HRPP administrators or staff and/or institutional leadership can join the SMART IRB Agreement, manage institutional information and user permissions, and track and document their institution’s reliance arrangements.

Legacy

If your institution has not yet joined SMART IRB Agreement V3.0 (but participates in V1.0 or V2.0), you may use the Reliance System to view arrangements documented in the legacy Online Reliance System, but your institution will not be able to initiate any new requests.

Glossary

Definitions related to the Reliance System and other SMART IRB terminology can be found in the SMART IRB Glossary.