Single IRB Review
SMART IRB helps streamline human subjects research, while ensuring robust protections for study participants. SMART IRB can be used for a range of research, from large, complex clinical trials to two-site collaborations. Clinical investigators can obtain trial results faster and, ultimately, speed development of new diagnostics, treatments, and preventative measures for patients.
How it works.
The Overall Principal Investigator (PI) of a multisite study works with the Points of Contact (POCs) for each participating institution involved in the study to determine an appropriate reliance arrangement. Together they will identify a Reviewing IRB and determine which institutions will rely upon that IRB for the review and oversight of the research. Additional details on these processes are available in the SMART IRB SOPs on "Establishing Reviewing IRBs and Relying Institutions" and "Initial Review Submission and Review Process." See the Resources page.
Additional detail on these processes is available in the SMART IRB SOPs on "Establishing Reviewing IRBs and Relying Institutions" and "Initial Review Submission and Review Process." See the Resources page.
Whether you are the Overall PI or a collaborating Site Investigator, if your study uses the SMART IRB Agreement, you assume specific responsibilities, in addition to your regulatory obligations as an investigator. For more information, see the roles and responsibilities described in the SMART IRB Standard Operating Procedures (SOPs).
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