Use SMART IRB to enable
single IRB review for your next study

More than 500 institutions have joined SMART IRB to simplify and speed single IRB review. As of January 25, 2018, all NIH-funded studies must use a single IRB for review and oversight of the research, but regardless of funding source or study type, SMART IRB can help support your IRB reliance arrangements.

Once your institution has joined SMART IRB, you can start using the SMART IRB Agreement to enable reliance arrangements with any other SMART IRB Participating Institutions. To find out if your institution has already joined, visit the Participating Institutions page or contact your IRB or human research protections program.

Follow these 3 easy steps to get started with SMART IRB

Overall Principal Investigators, connect with your institution’s POC(s) to determine an appropriate arrangement and discuss your responsibilities.

For more information, see:
Submit a reliance request
Request, track, and document reliance arrangements for your study with SMART IRB's Online Reliance System (or other process as indicated by your POC). First-time users, request access here.

For more information, see:
Online Reliance System Walkthrough
SMART IRB Support Center
Sample Reliance Request Form
Check out our Resources
SMART IRB resources for study teams will help you to understand and fulfill your responsibilities and regulatory obligations when serving as a Lead or Relying Site Study Team.

For more information, see:
Overall PI (and Lead Study Team) Checklist  
Relying Institution PI Checklist  
FAQs: Relying on an External IRB