Use SMART IRB to enable
single IRB review for your next study

More than 300 institutions have joined SMART IRB to simplify and speed single IRB review. Starting January 25, 2018, all NIH-funded studies must use a single IRB for review and oversight of the research, but regardless of funding source or study type, SMART IRB can help support your IRB reliance arrangements.

Once your institution has joined SMART IRB, you can start using the SMART IRB Agreement to enable reliance arrangements with any other SMART IRB Participating Institutions. To find out if your institution has already joined, visit the Participating Institutions page or contact your IRB or human research protections program.

Follow these 3 easy steps to get started with SMART IRB

1
Overall Principal Investigators, connect with your institution’s POC(s) to determine an appropriate arrangement and discuss your responsibilities.

For more information, see:
SMART IRB FAQs
SMART IRB SOP Manual
2
Submit a reliance request
Use SMART IRB’s Online Reliance System to request, track, and document reliance arrangements for your study (or other process as indicated by your POC). First-time users, request access here.

For more information, see:
Online Reliance System Walkthrough
SMART IRB Support Center
Sample Reliance Request Form
3
Check out our
Resources for study teams
SMART IRB tools and resources will help you to understand and fulfill your responsibilities and regulatory obligations when using the SMART IRB Agreement and serving as a Lead or Relying Site Study Team.

For more information, see:
Overall PI (and Lead Study Team) Checklist  
Relying Institution PI Checklist  
FAQs for Research Teams - Relying on an External IRB